> For the complete documentation index, see [llms.txt](https://nanovita.gitbook.io/nanovita-gitbook/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://nanovita.gitbook.io/nanovita-gitbook/scientific-basis-and-research-hypothesis/core-research-metrics.md).

# Core Research Metrics

The protocol is committed to precisely quantifying the biological effects of nanomaterials using the following multi-dimensional metrics:

* #### <mark style="color:$primary;">Heart Rate Variability (HRV)</mark>

Reflects autonomic nervous system balance, assessing stress, cardiovascular health, and recovery capacity.

* #### <mark style="color:$primary;">Sleep Quality</mark>

Deep sleep percentage, REM sleep efficiency, etc., directly related to physical recovery and cognitive function.

* #### <mark style="color:$primary;">Physiological Recovery Rate</mark>

The speed at which the body recovers from stress or exercise.

* #### <mark style="color:$primary;">Thermal Conduction and Body Temperature Stability</mark>

Evaluating the efficacy of nanomaterials in heat transfer and local temperature regulation.

* #### <mark style="color:$primary;">Subjective Health Perception</mark>

Collecting user self-reported health status data using validated scales.